192 research outputs found
A Biosystematic Study of the Genus Elymus (Gramineae: Triticeae) in Iowa
A study of the Iowa taxa of the genus Elymus is presented based upon extensive field and herbarium work. Characters used for analysis include anatomy, chromosome number, and morphology. Numerical analyses, distribution maps, and a key to species are included
The Parry Herbarium
The collections of Dr. C. C. Parry are of scientific importance because they include types of numerous plant species from the western United States and Mexico. The Parry herbarium, presently housed at Iowa State University, includes about 18,000 specimens. Earlier reports indicated the Parry collection numbered 30,000 specimens and \u27\u27not less than 15,000 species.\u27\u27 A brief history of the collection is reported. It is probable that Parry\u27s partial dispersal of his collection and his inadequate record keeping resulting in an overestimation of the number of his specimens are cause for the conflicting figures in the literature
Scalable detection of semantic clones
Several techniques have been developed for identifying similar code fragments in programs. These similar fragments, referred to as code clones, can be used to identify redundant code, locate bugs, or gain insight into program design. Existing scalable approaches to clone detection are limited to finding program fragments that are similar only in their contiguous syntax. Other, semantics-based approaches are more resilient to differences in syntax, such as reordered statements, related statements interleaved with other unrelated statements, or the use of semantically equivalent control structures. However, none of these techniques have scaled to real world code bases. These approaches capture semantic information from Program Dependence Graphs (PDGs), program representations that encode data and control dependencies between statements and predicates. Our definition of a code clone is also based on this representation: we consider program fragments with isomorphic PDGs to be clones. In this paper, we present the first scalable clone detection algorithm based on this definition of semantic clones. Our insight is the reduction of the difficult graph similarity problem to a simpler tree similarity problem by mapping carefully selected PDG subgraphs to their related structured syntax. We efficiently solve the tree similarity problem to create a scalable analysis. We have implemented this algorithm in a practical tool and performed evaluations on several million-line open source projects, including the Linux kernel. Compared with previous approaches, our tool locates significantly more clones, which are often more semantically interesting than simple copied and pasted code fragments
Trust, Trust Repair, and Public Health: A Scoping Review Protocol
Trust can be defined as âa willingness to be vulnerable to another for a given set of tasksâ and thus, trust and public health are inextricably linked. State actors are key participants in population health, organizing, among other things, mandates and guidelines that target health behaviors and encourage the uptake of medicines, screenings, diagnostics, and control of health conditions. Effective implementation of these crucial, government-sponsored health efforts is conditional on the publicâs belief that the state is trustworthy and has one\u27s best interest in mind â positioning trust in government as a central determinant of public health. Trusting relationships between patients, health systems, and health care providers are also essential, as high-quality, safe care and adherence with healthcare professionalsâ recommendations heavily depend upon trust. In many countries, trust in government and health care providers are inseparable, as governments are the primary providers of healthcare.
Despite these critical relationships, existing studies that link trust and public health outcomes often focus on contemporaneous factors, many of which are endogenous to public health outcomes (e.g., support for the incumbent political party). For example, Sopory and colleagues reported a comprehensive examination of the phenomenon of trust during public health emergency events among 68 studies from 28 countries that included individuals who were directly affected by a public health emergency. Importantly, no studies from South America or Africa were included. The shortage of research on the sociostructural, historical, economic, and political sources of low trust limits our understanding of how trust deficits might be remedied so as to improve population health. Understanding why trust is low as well as how to repair trust are thus of critical importance
Approaches to âvulnerabilityâ in eight European disaster management systems
Orru, K., Hansson, S., Gabel, F., Tammpuu, P., KrĂźger, M., Savadori, L., Meyer, S.F., Torpan, S., Jukarainen, P., Schieffelers, A., Lovasz, G. and Rhinard, M. (2022), Approaches to âvulnerabilityâ in eight European disaster management systems. Disasters, 46: 742-767. https://doi.org/10.1111/disa.12481While social vulnerability in the face of disasters has received increasing academic attention, relatively little is known about the extent to which that knowledge is reflected in practice by institutions involved in disaster management. In this study, we chart the practitionersâ approaches to disaster vulnerability in eight European countries: Germany, Italy, Belgium, Hungary, Sweden, Norway, Finland, and Estonia. The study draws from a comparative document analysis and 95 interviews with disaster managers and reveals significant differences across countries in terms of the ontology of vulnerability, its sources, reduction strategies, and the allocation of related duties. To advance the debate and provide conceptual clarity, we put forward a model for explicating different understandings of vulnerability along the dimensions of human agency and technological structures as well as social support through private relations and state actors.acceptedVersio
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Small RNA pathway genes identified by patterns of phylogenetic conservation and divergence
Genetic and biochemical analyses of RNA interference (RNAi) and microRNA (miRNA) pathways have revealed proteins such as Argonaute/PIWI and Dicer that process and present small RNAs to their targets. Well validated small RNA pathway cofactors, such as the Argonaute/PIWI proteins show distinctive patterns of conservation or divergence in particular animal, plant, fungal, and protist species. We compared 86 divergent eukaryotic genome sequences to discern sets of proteins that show similar phylogenetic profiles with known small RNA cofactors. A large set of additional candidate small RNA cofactors have emerged from functional genomic screens for defects in miRNA- or siRNA-mediated repression in C. elegans and D. melanogaster1,2 and from proteomic analyses of proteins co-purifying with validated small RNA pathway proteins3,4. The phylogenetic profiles of many of these candidate small RNA pathway proteins are similar to those of known small RNA cofactor proteins. We used a Bayesian approach to integrate the phylogenetic profile analysis with predictions from diverse transcriptional coregulation and proteome interaction datasets to assign a probability for each protein for a role in a small RNA pathway. Testing high-confidence candidates from this analysis for defects in RNAi silencing, we found that about half of the predicted small RNA cofactors are required for RNAi silencing. Many of the newly identified small RNA pathway proteins are orthologues of proteins implicated in RNA splicing. In support of a deep connection between the mechanism of RNA splicing and small RNA-mediated gene silencing, the presence of the Argonaute proteins and other small RNA components in the many species analysed strongly correlates with the number of introns in that species
The Effect of Body Size on Countermovement Jump Kinetics in Children aged 7 to 11 years
The purpose this study was to examine the effect of body size oncountermovement jump (CMJ)kinetics in children.Participants(n = 160) aged 7-11 years, divided equally by sex and into primary school year groups(years 3, 4, 5 and 6), each performedone CMJ on aforce platform. The variables bodyweight(BW), peak force (Fmax), in-jump minimum force (IMF), in-jump vertical force range (IFR) and basic rate of force development (BRFD)wereattained from the force-time history and then subsequently scaled to account for body size. A significant age, sex and interaction effect werefound for theabsolutevariables BW, IMF, Fmaxand IFR (P 0.05). No significant age or sex differences were observed for normalised or allometrically scaled values(P > 0.05). The results indicate thatgirls and boys can be grouped together but that body size must be accounted for to enable accurate conclusions to be drawn independent of growth.Bodysizesignificantlyeffects the representation of CMJ kinetic results and therefore, future studies should report both absolute and scaled values.Future research should developan age-appropriate criterion method for children in order to determine processed CMJ variables to further investigate neuromuscular performance of children
Evolution of white matter damage in amyotrophic lateral sclerosis
Objective
To characterize disease evolution in amyotrophic lateral sclerosis using an eventâbased model designed to extract temporal information from crossâsectional data. Conventional methods for understanding mechanisms of rapidly progressive neurodegenerative disorders are limited by the subjectivity inherent in the selection of a limited range of measurements, and the need to acquire longitudinal data.
Methods
The eventâbased model characterizes a disease as a series of events, each comprising a significant change in subject state. The model was applied to data from 154 patients and 128 healthy controls selected from five independent diffusion MRI datasets acquired in four different imaging laboratories between 1999 and 2016. The biomarkers modeled were mean fractional anisotropy values of white matter tracts implicated in amyotrophic lateral sclerosis. The cerebral portion of the corticospinal tract was divided into three segments.
Results
Application of the model to the pooled datasets revealed that the corticospinal tracts were involved before other white matter tracts. Distal corticospinal tract segments were involved earlier than more proximal (i.e., cephalad) segments. In addition, the model revealed early ordering of fractional anisotropy change in the corpus callosum and subsequently in long association fibers.
Interpretation
These findings represent dataâdriven evidence for early involvement of the corticospinal tracts and body of the corpus callosum in keeping with conventional approaches to image analysis, while providing new evidence to inform directional degeneration of the corticospinal tracts. This dataâdriven model provides new insight into the dynamics of neuronal damage in amyotrophic lateral sclerosis
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